Browsing: Health

INDIANAPOLIS, December 12, 2025: Eli Lilly and Co. announced that its next-generation obesity drug, retatrutide, achieved significant weight loss and reduced knee pain in a late-stage Phase 3 trial, underscoring its potential as a major advance in obesity and osteoarthritis treatment. The TRIUMPH-4 study evaluated retatrutide, a triple-hormone receptor agonist that activates GLP-1, GIP, and glucagon pathways, in adults with obesity and knee osteoarthritis. Participants receiving the highest dose of the drug lost an average of 28.7 percent of their body weight after 68 weeks of treatment, equivalent to approximately 71 pounds. Those receiving placebo lost an average of 2.1 percent…

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